Advances for a healthier future.
Women who consistently met physical activity guidelines throughout middle age had half the risk of dying from any cause compared to women who remained inactive, according to a paper published in PLOS Medicine by Binh Nguyen of the University of Sydney, Australia, and colleagues. Physical activity is known to provide numerous health benefits and to reduce the risk of chronic diseases and premature mortality. However, most prior studies have measured physical activity at only a single point in time, which fails to capture how activity levels change over time.
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A team of cancer genomics scientists from The University of Manchester and The Institute of Cancer Research, London, forensically examined the genetic make-up of tumors in 16 different cancers. Their findings, which have been published in Nature Genetics, are the culmination of six years of research and could significantly increase the number of cancer patients eligible for targeted and immune-based treatments.
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An international research collaboration led by Queen Mary University of London and University of the Witwatersrand (Wits) in South Africa has published the most comprehensive genomic investigation of kidney function ever conducted in African populations. The study sheds new light on the genetics of chronic kidney disease (CKD) across diverse African populations and will support future work aimed at improving prevention, diagnosis and treatment of kidney disease among these populations and worldwide.
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In a new study published in The Lancet Digital Health, scientists at the USC Mark and Mary Stevens Neuroimaging and Informatics Institute (Stevens INI) have discovered that the brains of people who experience severe physical impairment after a stroke may reorganize themselves in unexpected ways, showing signs of "younger" brain structure in undamaged regions as they adapt to injury.
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The heart's ability to use oxygen efficiently is a critical indicator of its health, but tests to measure this function have drawbacks that can limit their use. A new Cedars-Sinai Health Sciences University study found that a new MRI system developed at Cedars-Sinai might overcome this challenge. The findings, published in Science Translational Medicine, could one day improve management of heart failure, in which the heart fails to pump enough blood to meet the body's need for blood and oxygen.
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